Welcome

Activity Description

This multimedia activity will use a combination of expert presentations of clinical data in conjunction with patient case reports to discuss the treatment of chronic graft-versus-host disease (GvHD) in transplantation through cellular therapy. Leading researchers will discuss patient case scenarios and data on the treatment of GvHD in BMT patients, and in the similarities found in patients receiving transplants for solid organs such as heart and lungs. The target audience is transplantation and hematology specialists.

CME Information

Learning Objectives

Upon completion of this activity, participants should be better able to:

• Understand and explain the prevalence of GvHD in transplant patients
• State the current therapy options for treating chronic GvHD
• Identify potential future treatment options for treating chronic GvHD
  
• Assess the similarities in treatment of the BMT patient and patient and in treating patients with solid organ tumors
• Analyze the need for and possible design of further clinical trials on GvHD
  

Accreditation Statement

The Medical College of Wisconsin is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Designation of Credit Designation

The Medical College of Wisconsin designates this educational activity for a maximum of 1.0 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Faculty Disclosure

Consistent with the current Accreditation Council for Continuing Medical Education policy, the CME Provider must be able to show that everyone who is in a position to control the content of an individual educational activity has disclosed all relevant financial relationships. The CME Provider has a mechanism in place to identify and resolve any conflicts of interest discovered in the disclosure process. The presenting faculty members have all made the proper disclosures, and the following relationships are relevant:

Mark L. Barr, MD: has disclosed no relevant financial relationships.

Paul A. Carpenter, MBBS: has disclosed no relevant financial relationships.

James L.M. Ferrara, MD: has received honoraria and research support from Therakos; is on the speaker’s bureau and is an investigator for Therakos.  

Off-label/Investigational Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the Medical College of Wisconsin, Carden Jennings Publishing, or Therakos, Inc. Before prescribing any medication, physicians should consult primary references and full prescribing information. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings. Further, participants should appraise the information presented critically and are encouraged to consult appropriate resources for any product or device mentioned in this program.

Faculty

James L.M. Ferrara, MD, Program Chair
Professor of Internal Medicine
Director of Combined Blood and Marrow Transplant Program
University of Michigan Cancer Center
Ann Arbor, Michigan


Mark L. Barr, MD
Professor of Cardiothoracic Surgery
Co-Director, Heart and Lung Transplantation and Mechanical Circulatory Support Device Program
Director, Photopheresis Unit
University of Southern California Keck School of Medicine
Los Angeles, California
 

Paul A. Carpenter, MBBS
Associate Member
Fred Hutchinson Cancer Research Center
Associate Professor in Pediatrics
University of Washington
Seattle, Washington

Presentations

	ECP Treatment of Experimental Acute Gvhd: a Novel Murine Model James Ferrara, M.D. Professor of Internal Medicine Director of Combined Blood and Marrow Transplant Program University of Michigan Cancer Center Ann Arbor, Michigan View Presentation
	Photopheresis in Solid Organ Transplantation: Similarities to Treating the BMT Patient Mark L. Barr, MD Professor of Cardiothoracic Surgery Co-Director, Heart and Lung Transplantation and Mechanical Circulatory Support Device Program Director, Photopheresis Unit University of Southern California Keck School of Medicine Los Angeles, California View Presentation
	GvHD and the BMT CTN: What should future trials look like? Paul A. Carpenter, MBBS Associate Member Fred Hutchinson Cancer Research Center Associate Professor in Pediatrics University of Washington Seattle, Washington View Presentation
	Question and Answer Session Faculty View Presentation

CME Posttest