Oncogenic Pathways in Relapsed Acute Myeloid Leukemia: A Tale of Parallel Paths
Dr. Garrett-Bakelman proposes that AML relapse is shaped not only by genetic mutations and epigenetic alterations but also by transcriptional regulators that may independently promote tumor fitness and survival. This multifaceted understanding underscores the complexity of AML and the need for diverse therapeutic approaches to improve outcomes for relapsed patients.