Presenters and Affiliations:

  • Mary Helen Witt, MD – Clinical Faculty, UVA Community Oncology
  • Emily C. Ayers, MD, MSCE – Assistant Professor of Medicine, Division of Hematology/Oncology
  • Craig A. Portell, MD – Associate Professor of Medicine, Division of Hematology/Oncology

    Outline of Topics Presented:

    • Introduction and Overview: The impact of CLL and therapeutic challenges.
    • Case Studies and Treatment Strategies: Discussion of specific patient cases, their treatment history, and management strategies.
    • COVID-19 and CLL Treatment: Addressing treatment choices in the era of COVID-19, including vaccine response and considerations.
    • Mortality and Hospitalization Rates: Data on CLL patients’ outcomes during COVID-19.
    • Minimal Residual Disease (MRD) Testing: Techniques and significance in treatment planning.
    • BTK Inhibitors and Venetoclax: Discussion of their use, impact on MRD, and patient management.
    • Clinical Decision Making: Approaches to treatment alterations based on MRD results and patient conditions.
    • Future Directions in CLL Management: Insights into ongoing studies and evolving treatment strategies.

      This educational video provides a comprehensive overview of the current landscape in CLL treatment, highlighting the challenges and advances in therapy, especially in the context of the COVID-19 pandemic. The presenters, all experts in the field of hematology and oncology, offer valuable insights into patient management, evolving treatments, and the importance of MRD in guiding therapy decisions.

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